Phenolic profiles, antimicrobial and cytotoxic properties of both micropropagated and naturally growing plantlets of calamintha sylvatica subsp. sylvatica Bromf.

9Citations
Citations of this article
5Readers
Mendeley users who have this article in their library.

Abstract

A rapid micropropagation protocol was designed to produce Calamintha sylvatica plantlets by using nodal segments as explants for the shoot formation. 6-BA favored the highest shoot formation and biomass yield, whilst kinetin was found superior for the highest shoot length (38.97 ± 2.85 mm) and node numbers (2.89 ± 0.63). Rosmarinic acid was detected as major phenolic acid, ranging from 7.59 mg/100 g to 81.44 mg/100 g. Hexane extracts from natural and in vitro propagated plantlets showed activity only against Staphylococcus aureus ATCC 25923 with MIC values at 6.25 and 3.33 m/mL, respectively while in the latter case, extracts from natural plantlets exerted higher cytotoxic activity than those of micropropagated ones (IC50 values were 83 μg/mL and 98 μg/mL on HeLa cells, respectively). C. sylvatica showed high micropropagation performance and produced remarkable amount of rosmarinic acid in vitro as well as antimicrobial and cytotoxic effect.

Cite

CITATION STYLE

APA

Cüce, M., Bekircan, T., Laghari, A. H., Sökmen, M., Sökmen, A., Önay Uçar, E., & Kiliç, A. O. (2019). Phenolic profiles, antimicrobial and cytotoxic properties of both micropropagated and naturally growing plantlets of calamintha sylvatica subsp. sylvatica Bromf. Notulae Botanicae Horti Agrobotanici Cluj-Napoca, 47(4), 1145–1152. https://doi.org/10.15835/nbha47411474

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free