Oncologic and functional results of open radical prostatectomy as treatment of prostate cancer in a cohort of 1420 patients in Mexico City

Abstract

Open radical prostatectomy, since the beginning of the last century has been the gold standard in the localized prostate cancer treatment, and the platform from which minimally invasive procedures such as laparoscopy and robot-assisted surgery have reproduced its results. Objective: To evaluate the oncological outcomes and functional results of open radical prostatectomy in a cohort of 1420 patients in Mexico City. Material and methods: A retrospective cohort study of 1420 cases of patients with prostate cancer undergoing radical surgery for a single surgeon (ATG) in private care hospitals. Results: The median surveillance was 132 months (range 1 to 180 months). Cancer- specific survival was 95% (95% CI 96 to 9), 90% (95% CI 9 to 9), 7% (95% CI 6 to 9), % (95% CI to 6) and 0% (95% CI 79), at 5, 10 and 15 years respectively. The time free of biochemical progression decreased with greater the risk group, Gleason grade and extraprostatic extension at surgery time. Conclusion: Radical prostatectomy is up to now a procedure that offers cancer-specific survival as well as survival free of biochemical progression adequate to achieve adequate control of prostate neoplasia.