Intraosseous ancient Schwannoma: A rare case in the mandible and a literature review

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Abstract

Schwannoma, otherwise known as neurilemmoma, is a benign tumor that originates from Schwann cells. Ancient Schwannoma is a long-standing Schwannoma with degenerative and xanthomatous changes. The Head and neck region is one of the most common sites for nerve sheath tumors but Involvement of the jaw is a considerably infrequent event. We report a rare case of intraosseous ancient Schwannoma of the mandible in a 24-year-old male patient which was initially misdiagnosed with carcinoma. The clinical features, radiographic findings, and treatment plan are discussed. Furthermore, a thorough literature review demonstrated nine published cases of intra-osseous ancient Schwannoma with their summarized features. Recognition of various histopathologic features of ancient Schwannoma is essential to prevent over-treatment.

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Kardouni Khoozestani, N., Motiee-Langroudi, M., Salehi, A., & Ranji, P. (2021). Intraosseous ancient Schwannoma: A rare case in the mandible and a literature review. Rare Tumors, 13. https://doi.org/10.1177/20363613211026480

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