Maduramicin and tiamulin compatibility in broiler chickens

Abstract

A total of 480 1-day-old Hybro broiler chickens were divided into five treatment groups (A: unmedicated control, B: maduramicin, C: maduramicin + tiamulin, D: monensin + tiamulin and E: tiamulin) to study the effect on performance parameters, organ weights, blood haematology and biochemistry, and histopathology of liver and selected striated muscles, when maduramicin at 5 parts/I06and monensin at 100 parts/106were included in feed in starter and grower periods, and tiamulin 9 in water at 270 parts/106the recommended therapeutic level, from day 28 to 31. Performance parameters were significantly and negatively affected by monensin but not by maduramicin after treatment with tiamulin. Histopathological examination of striated muscles showed no incompatibility of maduramicin + tiamulin, while lesions were found in the monensin + tiamulin treated group. It is concluded that the use of tiamulin to a therapeutic level for 3 consecutive days is compatible with the simultaneous presence of maduramicin in the feed of broilers. © 1994, Taylor & Francis Group, LLC. All rights reserved.