Antibacterial Activity of Garlic Extract Against some Pathogenic Animal Bacteria

Abstract

The antimicrobial activity of garlic extract against Gram-positive and Gram-negative bacterialisolates was well studied. However, reports on antibacterial activity of garlic extract against somepathogenic bacteria in animals in Indonesia, are still limited. Therefore, the aim of this study wasto evaluate the antibacterial activity of water and ethanol extracts of garlic against Salmonella typhimuriumin chickens, and Streptococcus agalactie, Escherichia coli, and Staphylococcus aureus causingmastitis in dairy cows in Indonesia. A fi ltrate of fresh garlic was used to determine the antibacterialactivity against S. typhimurium at concentrations of 5%, 10%, 20%, 30%, and 40% w/v, whereas,the antibacterial activity of water and ethanol extracts was determined against S. agalactie, E. coli,and S. aureus at concentrations of 5%, 10%, 15%, 20%, and 25% w/v. Results showed that antibacterialactivity of 30% garlic fi ltrate was equivalent to 10% tetracycline. Meanwhile, antibacterial activity ofgarlic aqueous extract on mastitis bacteria was better than that of the garlic ethanol extract. Aqueousextract of garlic at 20% had the same antibacterial activity as 0.01% ampicillin on mastitis bacteria.Filtrates of fresh garlic can be used to inhibit growth of S. typhimurium and mastitis bacteria.