Journal Article

Preparation of functionalized indoles and azaindoles by the intramolecular copper-mediated carbomagnesiation of ynamides

Angewandte Chemie - International Edition (2013) 52(38) 10084-10088
DOI: 10.1002/anie.201304380
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Abstract

Variations on a theme: A mild and general intramolecular copper-mediated carbomagnesiation procedure for the synthesis of functionalized indoles as well as 4-, 5-, 6-, and 7-azaindoles starts from readily available ynamides. Subsequent reactions with various electrophiles provides polyfunctional N-heterocycles in good yields. © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

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Frischmuth, A., & Knochel, P. (2013). Preparation of functionalized indoles and azaindoles by the intramolecular copper-mediated carbomagnesiation of ynamides. Angewandte Chemie - International Edition, 52(38), 10084–10088. https://doi.org/10.1002/anie.201304380

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