Myocardial performance index derived from brachial-ankle pulse wave velocity: A novel and feasible parameter in evaluation of cardiac performance

Abstract

BackgroundRight brachial pre-ejection period (rbPEP), brachial-ankle pulse wave velocity (baPWV), and right brachial ejection time (rbET) can be automatically determined from an ABI-form device. The aims of this study are to test the applicability of baPWV-derived myocardial performance index (MPI) (defined as the ratio of rbPEP divided by its own s.d. baPWV divided by its own s.d. to rbET divided by its own s.d.) as an indicator of combined left ventricular (LV) systolic and diastolic functions.MethodsA sum of 215 patients were consecutively included. The rbPEP, baPWV, and rbET were measured using an ABI-form device and LV function was determined by echocardiography.ResultsAfter a multivariate analysis, diastolic blood pressure (Β = 0.220, P 0.001), LV ejection fraction (LVEF) (Β = 0.291, P< 0.001), transmitral E wave velocity (E) (Β = 0.106, P = 0.032), early diastolic mitral annular velocity (Ea) (Β = 0.142, P = 0.009), and ET obtained by tissue Doppler echocardiography (Β = 0.397, P 0.001) were the major determinants of baPWV-derived MPI. The area under the curve for rbPEP, baPWV, rbET, rbPEP/rbET, and baPWV-derived MPI in prediction of Ea 8 cm/s, E/Ea 10, or LVEF 50% were 0.69, 0.76, 0.67, 0.73, and 0.83, respectively.ConclusionsBaPWV-derived MPI had a significant correlation with echocardiographic LV diastolic and systolic function. It may be a novel and feasible indicator in assessment of global LV function. © 2009 American Journal of Hypertension, Ltd.