Neuroimaging results suggest the role of prediction in cross-domain priming

Abstract

The repetition of a stimulus leads to shorter reaction times as well as to the reduction of neural activity. Previous encounters with closely related stimuli (primes) also lead to faster and often to more accurate processing of subsequent stimuli (targets). For instance, if the prime is a name, and the target is a face, the recognition of a persons' face is facilitated by prior presentation of his/her name. A possible explanation for this phenomenon is that the prime allows predicting the occurrence of the target. To the best of our knowledge, so far, no study tested the neural correlates of such cross-domain priming with fMRI. To fill this gap, here we used names of famous persons as primes, and congruent or incongruent faces as targets. We found that congruent primes not only reduced RT, but also lowered the BOLD signal in bilateral fusiform (FFA) and occipital (OFA) face areas. This suggests that semantic information affects not only behavioral performance, but also neural responses in relatively early processing stages of the occipito-Temporal cortex. We interpret our results in the framework of predictive coding theories.