Abstract
The human gene coding for the apoferritin H subunit belongs to a complex multigene family constituted by the expressed gene and by an undefined number of pseudogenes. We have used a strategy based on PCR to amplify specifically the H pseudogenes from a sample of human genomic DNA. With this approach, three new H pseudogenes have been cloned and characterized by DNA sequence analysis. In addition, we have identified a new type of pseudogene, the size of which (700 bp) is caused by multiple deletion events in the putative coding region.
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CITATION STYLE
Quaresima, B., Tiano, M. T., Porcellini, A., D’Agostino, P., Faniello, M. C., Bevilacqua, M. A., … Costanzo, F. (1994). PCR analysis of the H ferritin multigene family reveals the existence of two classes of processed pseudogenes. PCR Methods and Applications, 4(2), 85–88. https://doi.org/10.1101/gr.4.2.85
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