Application of Nanocellulose Biocomposites in Acceleration of Diabetic Wound Healing: Recent Advances and New Perspectives

Abstract

Diabetes mellitus (DM) is a chronic health problem that increases the risk of infection and delays wound healing due to impairment of metabolic activity. Diabetic foot ulcers (DFUs), a chronic wound increases the risk of mortality. Finding the most appropriate wound dressings has been intensified with the increasing population and prevalence of chronic wounds. Nanofibers coated wound dressings have attracted more attention as innovative and biocompatible materials. Nanocellulose (NC) has been widely used as a reinforcing material to improve nanofibers’ mechanical and thermal properties. NC is biodegradable and derived from renewable sources and produced bionanocomposites with improved performance.