Morinda citrifolia mediated biogenic synthesis of selenium nanoparticles and evaluation of its antimicrobial and antioxidant activity

Abstract

Purpose : The aim of the study is to assess its potential to synthesize selenium nanoparticles (SeNPs) with Noni fruit extract and augment its antimicrobial and antioxidant activity. Materials and methods: The synthesized SeNPs were confirmed using UV-vis spectroscopy and transmission electron microscopy (TEM). Antimicrobial activity against S. mutans, S. aureus, E. faecalis, C. albicans was tested using agar diffusion; antioxidant potential assessed on 2,2-diphenyl-2-picrylhydrazyl hydrate oxidation. Results : UV-vis, and TEM confirmed the synthesis of SeNPs and revealed smooth spherical nanoparticles (25-100nm). SeNPs exhibited significant antimicrobial activity for the provided concentration against all organisms and excellent antioxidant potential in a dose dependent manner (84% inhibition/50 µl concentration). Conclusion : Morinda citrifolia augmented biogenic SeNPs is a cost effective yet efficient method and they show great potential as oral antimicrobial agent with superior antioxidant properties and is eco-friendly.