Platelet αiIbβ3 activation: Filling in the pieces

Abstract

In this issue of Blood, Kasirer-Friede and colleagues show that the adhesion and degranulation promoter protein (ADAP) promotes αIIbβ3 activation by presenting the cytoplasmic proteins talin and kindlin to the β3 cytoplasmic tail. © 2014 by The American Society of Hematology.