Exploring the Therapeutic Potential: Phytochemistry and Pharmacology of Bryophyllum pinnatum

Abstract

Bryophyllum pinnatum, a renowned medicinal plant with a rich history in various traditional medical practices, has been utilized for treating a range of ailments such as fever, smallpox, otitis, cough, asthma, headache, convulsion, and general debility. The plant's diverse secondary metabolites, including steroids, flavonoids, terpenoids, fatty acids, bufadienolides, proteins, peptides, vitamins, and polysaccharides, have been identified. Over the past thirty years, extensive research has unveiled the plant's pharmacological effects both in vivo and in vitro, demonstrating its antimicrobial, anti-ulcer, antihypertensive, antileishmanial, anti-cancer, antidiabetic, and immunomodulatory properties. This comprehensive review aims to provide a consolidated overview of Bryophyllum pinnatum, encompassing its traditional uses, phytochemistry, and pharmacological studies. By presenting a wealth of information, this paper seeks to inspire further exploration into the potential beneficial applications of the plant. Additionally, it sheds light on the clinical uses and prospects of Bryophyllum pinnatum, offering valuable insights for future research endeavors. Keywords: Bryophyllum pinnatum, Chemical Constituent, Biological activities, antioxidant effect, Therapeutic potential