Performance characteristics of an automated, high-throughput RT-PCR assay for the detection of Candida auris on 3-point and nasal swabs

Abstract

Candida auris is a multidrug-resistant yeast responsible for severe infections with high mortality rates. Rapid and accurate detection is critical for preventing the spread of this pathogen in healthcare settings. This study assesses the performance of an automated real-time PCR screening assay for detecting C. auri s using nasal and 3-point swabs. The findings demonstrate the assay's high sensitivity, specificity, and reproducibility, making it a valuable tool for infection control. By providing a reliable and efficient screening method, this assay can significantly enhance efforts to control C. auris outbreaks, ultimately improving patient outcomes and reducing the spread of this dangerous pathogen.