Oculogyric Crisis in Early Pregnancy: Lessons Learned From a Rare Adverse Effect of Metoclopramide

Abstract

Metoclopramide is a widely prescribed antiemetic, particularly in pregnancy, for managing nausea and vomiting. While it is considered safe in most cases, rare extrapyramidal side effects such as acute dystonia with oculogyric crisis can occur. Here, we present a case of a 12-week pregnant woman who developed acute dystonia with oculogyric crisis after treatment with metoclopramide. Oral trihexyphenidyl (Benzhexol) led to rapid symptom resolution. This case emphasizes the need for awareness of rare adverse drug reactions and the importance of early recognition to prevent further complications.