Synthesis and structure-activity relationships of novel nikkomycin analogs: inhibitors of the fungal cell wall biosynthesis enzyme chitin synthase.

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Abstract

A series of novel nikkomycin analogs, which inhibited chitin synthase, the fungal cell wall biosynthesis enzyme, has been synthesized and evaluated their inhibitory activities.

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Uda, J., Obi, K., Iwase, K., Sugimoto, O., Ebisu, H., & Matsuda, A. (1999). Synthesis and structure-activity relationships of novel nikkomycin analogs: inhibitors of the fungal cell wall biosynthesis enzyme chitin synthase. Nucleic Acids Symposium Series, (42), 13–14. https://doi.org/10.1093/nass/42.1.13

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