Collagen from marine source for regenerative therapy: A literature review

Abstract

All species of multicellular organisms are formed from connective tissue in which the main forming protein is collagen. Collagen is usually extracted from animal species and their waste products. Because of the prevalence of dangerous infectious diseases (zoonosis) and religious reasons in some countries, research is needed on other sources of non-mammalian natural biomaterials. At present, many bioactive material derived from marine source have been developed. Collagen derived from marine source has several advantages, namely good biocompatibility, low imunogenicity, high levels of direct cell adhesion, and high biodegradability. The excellent biocompatibility of marine collagen has shown its potential in tissue engineering and in regenerative therapy for biomaterial scaffolding.