Skene duct adenocarcinoma in a patient with an elevated serum prostate-specific antigen level: A case report

Abstract

Background: Female urethral carcinoma is a very rare disease that accounts for 0.02% of malignant diseases in female patients. Case presentation: A 70-year-old Asian Japanese woman with a urethral tumor was referred to our hospital to undergo further examination. Biopsy specimens showed urethral adenocarcinoma that was positive for prostate-specific antigen. Her serum prostate-specific antigen level before surgery was 34.4 ng/ml. Urethral tumor resection with pelvic lymph node resection was performed. Her serum prostate-specific antigen level decreased to < 0.01 ng/ml after surgery. Conclusions: We report a very rare case of Skene duct adenocarcinoma in a female patient with serum prostate-specific antigen elevation.