Phaeochromocytoma in children

Abstract

Four previously-unreported cases of phaeochromocytoma in children are described. Of these, two were successfully treated surgically, two died in hypertensive crisis and one was histologically malignant. In reviewing all cases reported in children (62 in all) 62 have been analysed regarding age and sex, 60 regarding site and multiplicity of tumours. Methods used in diagnosing and localizing phaeochromocytoma are described. Once diagnosed, the desirability of undertaking full surgical exploration of the posterior abdominal wall through an anterior approach without any pre-operative attempt to localize the tumour or tumours is discussed. The danger to life once the case has reached hospital and the great value of phentolamine preoperatively and of phentolamine and noradrenaline during operation are noted.