Tamanho de população ideal para mapeamento genético em famílias de irmãos completos

Abstract

The objective of this work was to evaluate the optimum size of populations for the study of genetic mapping of full sibling families, through data simulation of genome and populations. Parental genomes and population samples of full sibling families of both completely and non-completely informative types, were simulated. The generated samples had 100, 200, 400 and 600 individuals, with three linkage groups each, and 11 codominant multi-allelic molecular marks, spaced by ten centimorgans in each linkage group. One-hundred repetitions were accomplished by sample. In completely informative populations, the optimum size of 200 individuals is enough to rescue the original information, however, for the non-completely informative population, it is necessary a larger population, with 600 individuals.