Synthesis and Absolute Configuration of Neocnidilide

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Abstract

(—)-Neocnidilide (1), an antifungal substance isolated from Cnidium officinale Makino and its antipode 11 were respectively synthesized from (S)- and (R)-(E)-1-ethenylpentyl 2,4-pentadienoate (4) and (5) via the intramolecular Diels-Alder reaction. This synthesis established that the absolute configuration of 1 was 35 3aR. © 1987, Japan Society for Bioscience, Biotechnology, and Agrochemistry. All rights reserved.

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Suzuki, H., Tanaka, A., & Yamashita, K. (1987). Synthesis and Absolute Configuration of Neocnidilide. Agricultural and Biological Chemistry, 51(12), 3369–3373. https://doi.org/10.1271/bbb1961.51.3369

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