CA 125 in biological fluids

Abstract

CA 125 is one of the most popular tumor markers usually synthetized by normal and malignant cells of different origins. Increased levels can be found in both benign and malignant conditions in fluids with different origins such as pleural effusion, ascites, ovarian cysts fluids, amniotic fluid and even pancreatic cyst fluids. This is a literature review of the largest studies regarding various conditions in which increased levels of CA 125 can be found and their clinical significance.