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A versatile synthetic extracellular matrix mimic via thiol-norbornene photopolymerization

Advanced Materials (2009) 21(48) 5005-5010
DOI: 10.1002/adma.200901808
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Abstract

Step-growth, radically mediated thiolnorbornene photopolymerization is used to create versatile, stimuli-responsive poly(ethylene glycol)-co-peptide hydrogels (see image). The reaction is cytocompatible and allows for the encapsulation of human mesenchymal stem cells with a viability greater than 95%. Cellular spreading is dictated via three-dimensional biochemical photopatterning. © 2009 WILEY-VCH Verlag GmbH & Co. KGaA.

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Fairbanks, B. D., Schwartz, M. P., Halevi, A. E., Nuttelman, C. R., Bowman, C. N., & Anseth, K. S. (2009). A versatile synthetic extracellular matrix mimic via thiol-norbornene photopolymerization. Advanced Materials, 21(48), 5005–5010. https://doi.org/10.1002/adma.200901808

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