Heat inactivation of serotype 1 infectious bursal disease virus

Abstract

Heat inactivation curves for infectious bursal disease virus serotype 1 (IBDV) strain 52/70 in bursal homogenate supernatant were constructed for 70°C, 75°C and 80°C. Biphasic, multiple kinetics curves were produced with an initial rapid drop in infectivity followed by a more gradual decline. In this second phase the approximate times taken to reduce the infectivity by 1 log10 at each temperature were: 70°C (18.8 min), 75°C (11.4 min) and 80°C (3.0 min), confirming the heat resistance of this virus.