Glycated Hemoglobin A1c and Diabetes Complications

Abstract

Objectives: This study aimed to highlight the association of HbA1c with diabetic related complications. Material and Methods: This retrospective study has been conducted in endocrinology department of Alnoor Specialist Hospital, Makkah, Saudi Arabia, from January 2007 to December 2009. Data has been collected from diabetic patients' files that were referred to the diabetes outpatient department either because of consultation from other health care centers or from other departments of the same hospital due to diabetes related complications. Patients' files were reviewed for levels of HbA1c and diabetes related complications. The values of HbA1c were considered at the time of diagnosis of complications. Results: The total study subjects were 110 with mean HbA1C was 7.3 with range (5.9-11.3). Only significant association between the HbA1c and diabetic septic foot was seen (p value=0.037) while values of regression showed that HbA1c is best correlated with cardiovascular disease (R=0.39, Beta =0.004 and p-value = 0.104). Conclusion: Our study results showed insignificant association between the HbA1c and diabetic complications except that of with diabetic septic foot. [ABSTRACT FROM AUTHOR]