para-sulphonato-calix[n]arenes as selective activators for the passage of molecules across the Caco-2 model intestinal membrane

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Abstract

The passage of Lucifer Yellow across the Caco-2 intestinal model membrane has been studied for the para-sulphonato-calix[n]arenes, the results show that para-sulphonato-calix[4]arene and para-sulphonato-calix[8]arene activate membrane passage when used simultaneously with a transport probe, Lucifer Yellow, whereas para-sulphonato-calix[6]arene has no effect.

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Roka, E., Vecsernyes, M., Bacskay, I., Félix, C., Rhimi, M., Coleman, A. W., & Perret, F. (2015). para-sulphonato-calix[n]arenes as selective activators for the passage of molecules across the Caco-2 model intestinal membrane. Chemical Communications, 51(45), 9374–9376. https://doi.org/10.1039/c5cc01777g

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