For Early Diagnosis of Neurodegenerative Diseases: Acting of Biomarkers

Abstract

Neurodegenerative disease is a kind of progressive and incurable diseases caused by neuron degeneration and leads to cognitive impairment and dyskinesia. The prevalence of neurodegenerative diseases increases with age and the age of neurodegenerative diseases tends to be younger. Biomarkers, discovered from blood or cerebrospinal fluid to imaging, are helpful in diagnosis of neurodegenerative diseases, especially in early and differential diagnosis, which can help choose the proper treatment. This review will focus on biomarkers used in Alzheimer's disease, Parkinson's disease and Prion disease diagnosis and recent advancements in biomarker discovery.