The in vivo activity of olamufloxacin (HSR-903) in systemic and urinary tract infections in mice

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Abstract

The in vivo activity of olamufloxacin (HSR-903), a new fluoroquinolone, was evaluated and compared with ciprofloxacin, sparfloxacin and levofloxacin. Olamufloxacin was active against systemic infection in mice inoculated with both Gram-positive and -negative bacteria. Olamufloxacin had equal efficacy for experimental urinary tract infections in mice caused by Pseudomonas aeruginosa.

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Yoshizumi, S., Takahashi, Y., Murata, M., Domon, H., Furuya, N., Ishii, Y., … Yamaguchi, K. (2001). The in vivo activity of olamufloxacin (HSR-903) in systemic and urinary tract infections in mice. Journal of Antimicrobial Chemotherapy, 48(1), 137–140. https://doi.org/10.1093/jac/48.1.137

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