Sequence-specific cleavage of human telomere DNA by G-quadruplex formation.

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Abstract

In the current study, we reported that oligonucleotide with EDTA-Fe at 5' end causes a sequence specific break in human telomeric DNA strand by G-quadruplex formation.

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Xu, Y., Hirohata, Y., & Komiyama, M. (2007). Sequence-specific cleavage of human telomere DNA by G-quadruplex formation. Nucleic Acids Symposium Series (2004), (51), 199–200. https://doi.org/10.1093/nass/nrm100

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