Structure and structure-function relationships in gonadotropins

Abstract

Pituitary gonadotropins (LH and FSH) as well as chorionic gonadotropins (CG) are glycoprotein hormones and, as such, are the most complex molecules with hormonal activity known so faR. Because of their structural complexity and their primordial role in gonadal functions, the structure-function relationships of gonadotropins are of utmost interest for both the protein chemist and the reproductive endocrinologist.