Absence of the 9q+ chromosome in Ph1 negative chronic myelogenous leukaemia

Abstract

Bone marrow chromosomes from four patients with Ph1 negative chronic myelogenous leukaemia were examined with quinacrine fluorescence. The marrow cells of all four patients showed an apparently normal karyotype. This karyotype is different from that of the Ph1 positive variant in which a possible translocation (9q+;22q-) was observed.