Efficacy of mineral cationic carrier against sulphur mustard in skin decontamination

Abstract

The aim of this study was to evaluate decontamination (absorption) efficacy of a preparation called Mineral Cationic Carrier (MCC®) against skin contamination with sulphur mustard in vivo. MCC® is a synthetic preparation with known ion exchange, absorption efficiency, and bioactive potential. CBA mice were applied increasing doses of sulphur mustard on their skin and MCC® was administered immediately after skin contamination. The results have confirmed the decontamination efficacy of MCC® preparation, corresponding to 8.4 times the LD50 of percutaneous sulphur mustard, and call for further investigation.