Do count-based differential expression methods perform poorly when genes are expressed in only one condition?

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Abstract

A response to 'Comprehensive evaluation of differential gene expression analysis methods for RNA-seq data' by Rapaport F, Khanin R, Liang Y, Pirun M, Krek A, Zumbo P, Mason CE, Socci ND and Betel D in Genome Biology, 2013, 14:R95

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Zhou, X., & Robinson, M. D. (2015, October 8). Do count-based differential expression methods perform poorly when genes are expressed in only one condition? Genome Biology. BioMed Central Ltd. https://doi.org/10.1186/s13059-015-0781-3

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