Recent progress in the fluorescent probe based on spiro ring opening of xanthenes and related derivatives

Abstract

Fluorescent probe technology has specially outstanding function in the track of the heterogeneous recognition behaviors and the information from the internal status of the complicated biological and environmental systems. The spiral ring structure of xanthene and related derivatives which substrate triggered fluorescent switching is the most extensively used model in construction of novel photosensitive fluorescent probes. In recent years, design, synthesis and functional regulation and control of this type of probe are active sub-discipline with continuous breakthroughs. In this paper, the most recent advances in the detection of different metal cations, pH deviations, anions which based on xanthene and related derivatives are reviewed. The construction of xanthene based fluorescent probes, the recognition mechanisms and the application in bioimaging and environmental monitoring are particularly highlighted. © 2014 Chinese Chemical Society & SIOC, CAS.