Galanin message-associated peptide suppresses growth and the budded-to-hyphal-form transition of Candida albicans

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Abstract

The expression of the mRNA encoding galanin message-associated peptide (GMAP) in human keratinocytes is upregulated by lipopolysaccharides and exposure to Candida albicans. GMAP has growth-inhibiting activity against C. albicans and inhibits the budded-to-hyphal-form transition, establishing GMAP as a possible new component of the innate immune system. Copyright © 2007, American Society for Microbiology. All Rights Reserved.

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Rauch, I., Lundström, L., Hell, M., Sperl, W., & Kofler, B. (2007). Galanin message-associated peptide suppresses growth and the budded-to-hyphal-form transition of Candida albicans. Antimicrobial Agents and Chemotherapy, 51(11), 4167–4170. https://doi.org/10.1128/AAC.00166-07

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