Atividade in vitro de anti-helmínticos sobre larvas infectantes de nematódeos gastrintestinais de caprinos, utilizando a técnica de coprocultura quantitativa (Ueno, 1995)

Abstract

This work was achieve with the objective of the compare the action ovi-larvicida in vitro of anthelmintic, using the caprine gastrointestinal nematodes quantitative faeces culture technic. Seven anthelmintics were testes, in the experiment: albendazole, albendazole sulfoxide, fenbendazole, oxfendazole, ivermectin, levamisole and closantel. The used goats for obtain of the faeces, had been kept inthe school of the Medicina Veterinary/University Federal of Bahia(UFBA), for one year and middle, without receiving anthelmintics. The anthelmintics. were dilutes in destiled water, from the original solution, initiating itsell of the dilution 1:10 until 1:5120, perform in the total of the 10 dilutions. The faecal culture prepared with 2g of the faeces, 2g of the sawing and 2ml of the distil water ar the differents dilutions of the anthelmintics, had been maintained the 340C, for seven days, for obtain of the infective larvae of the gastrointestinal nematodes. The ivermectin presented ovilarvicida action better, with reduction genus of the larvae Haemonchus, Trichostrongylus and Oesophagostomum (L3), white the fenbendazole was the product with action smaller for the genus Haemonchus and Trichostrongylus. For the genus Oesophagostomum, the products albendazole, fenbendazole, oxfendazole and albendazole sulfoxide, had full eliminated the population of this species. The products between ivermectin, levamisole and closantel, the ivermectin presented action better ovi-larvicida for eggs of the Oesophagostomum.