Low temperature plasma causes double-strand break DNA damage in primary epithelial cells cultured from a human prostate Tumor

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Abstract

Research in the new field of plasma medicine continues to demonstrate the efficacy of low temperature plasmas (LTPs) for numerous biomedical applications. Responses such as reduction in cell viability and cell death for cancer therapy, cell proliferation for wound healing, and bacterial inactivation have been observed as a result of plasma treatment. In this paper, we applied LTP to prostate cancer primary cells derived from patient tumour tissue to inflict irreparable DNA damage.

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Hirst, A. M., Frame, F. M., Maitland, N. J., & O’Connell, D. (2014). Low temperature plasma causes double-strand break DNA damage in primary epithelial cells cultured from a human prostate Tumor. IEEE Transactions on Plasma Science, 42(10), 2740–2741. https://doi.org/10.1109/TPS.2014.2351453

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