Detection of human herpesvirus 6 and Varicella-zoster virus in tear fluid of patients with Bell's palsy by PCR

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Abstract

Human herpesvirus 6 DNA was detected by PCR in the tear fluid of 7 (35%) of 20 patients with Bell's palsy and of 1 (5%) of 20 healthy controls. Varicella-zoster virus was detected by PCR in the tear fluid of 2 of 20 Bell's palsy patients but in none of the tear fluids from 20 healthy controls. These findings suggest an association between human herpesviruses and Bell's palsy.

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Pitkäranta, A., Piiparinen, H., Mannonen, L., Vesaluoma, M., & Vaheri, A. (2000). Detection of human herpesvirus 6 and Varicella-zoster virus in tear fluid of patients with Bell’s palsy by PCR. Journal of Clinical Microbiology, 38(7), 2753–2755. https://doi.org/10.1128/jcm.38.7.2753-2755.2000

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