Abstract
A new antimycin group antibiotic, antimycin A9, was isolated from a cultured broth of Streptomyces sp. K01-0031 together with antimycins A3a, A3b, A4, and A7, and flazin methyl ester. Antimycin A9 is the first antimycin having an aromatic 8-acyl residue. It showed potent nematocidal and insecticidal activities against Caenorhabditis elegans and Artemia salina, respectively. It inhibited bovine heart NADH oxidase at nanomolar level like other known antimycins. © Japan Antibiotics Research Association.
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Shiomi, K., Hatae, K., Hatano, H., Matsumoto, A., Takahashi, Y., Jiang, C. L., … Omura, S. (2005). A new antibiotic, antimycin a9, produced by Streptomyces sp. K01-0031. Journal of Antibiotics, 58(1), 74–78. https://doi.org/10.1038/ja.2005.10
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