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Background: Diverticular disease of the colon is more common in the Western world, compared with non-Western countries. Aim: To investigate the risk of diverticular disease in immigrants of diverse ethnicity and in different phases of acculturation. Methods: Socio-demographic indicators and the risk of diverticular disease were investigated. The study population was a prospectively followed national cohort of 4 million residents born between 1925 and 1965. Risk ratios (RRs) of hospital admissions and deaths because of diverticular disease and acute diverticulitis from 1991 through 2000 were calculated. Results: The risk of hospital admission because of diverticular disease, after adjustment for age, sex and socio-economic indicators, was lower in non-Western immigrants (RRs = 0.5-0.7) compared with natives and the risk increased with time after the settlement. Women of all origins had a higher risk compared with men (RR = 1.5). This sex-difference increased with age (P < 0.001). Socio-economic status, residency or housing situation were not risk factors. Conclusion: This population-based study found that immigrants from non-Westernized countries had lower relative risks for hospitalization because of diverticular disease than natives, but the risk increased during a relatively short period of time after settlement. Diverticular disease of the colon appears to be an acquired disorder and acculturation to a Western lifestyle has an impact on the risk. © 2006 The Authors.
Hjern, F., Johansson, C., Mellgren, A., Baxter, N. N., & Hjern, A. (2006). Diverticular disease and migration - The influence of acculturation to a Western lifestyle on diverticular disease. Alimentary Pharmacology and Therapeutics, 23(6), 797–805. https://doi.org/10.1111/j.1365-2036.2006.02805.x