A case of wegener's granulomatosis

Abstract

Sixty-two years old male farmer was admitted to our clinic because of nasal obstruction, nasal discharge, nose-bleed and some swelling of the cheek on the right side for 4 months. Complete maxillectomy with radical neck dissection was performed under the diagnosis of the malignant tumor of the right maxilla. The specimen from the tumor revealed the necrotizing granulomatous lesions with angitis. Hematuria, albumiuria and azotemia occurred in the postoperative course. A specimen of the kidney biopsy showed granulomatous glomerulonephritic findings. Antibiotics and predonine were administered without effects. He died 6 months after the onset of the disease. Review of the literature in Japan and description on the clinical features of Wegener's Granulomatosis are presented. (author' abstract). © 1962, The Oto-Rhino-Laryngological Society of Japan, Inc. All rights reserved.