Primary malignant melanoma of the esophagus: A case report and review of the literature

Abstract

Primary malignant melanoma of the esophagus (PMME) is a rare malignancy and the prognosis is typically poor. There is currently a lack of appropriate treatment strategies and clear guidance. The current study presents the case of a 65‑year‑old female with a two‑month history of progressive dysphagia, the investigations of which resulted in a diagnosis of PMME. The patient was treated with a radical transhiatal esophagectomy with subcarinal lymphadenectomy followed by combined chemoimmunotherapy. The patient remains alive with no evidence of tumor progression at the 12‑month follow‑up. The purpose of the present study was to report a new case and to review the recent relevant literature regarding the treatment of PMME.