A review on obesity its pathophysiology, and role of serum lactate and cystatin C biomarkers in obesity

Abstract

Obesity and its prevalence is rising continuously in developed as well as developing countries. High body mass index is a risk factor for various metabolic derangements which includes hypertension, dyslipidemia, stroke, gall bladder disease, diabetes and coronary artery disease and therefore the associated morbidity, mortality and medical costs are expected to increase as well. Lactate and Cystatin C are known to release from adipose tissues and may both contribute to metabolic derangements in obese patients. So, the aim is to study the role of serum Lactate and Cystatin C in obesity. In this article we will review 1) The pathophysiology of obesity 2) role of lactate and Cystatin C in obesity.