Efficacy of a plant-based dental gel for chronic simple marginal gingivitis: a clinical trial

Abstract

High prevalence of inflammatory periodontal diseases in young people along with unfavourable outcomes and long-term consequences cause great damage to health, thereby determining the importance and urgency of this problem in modern dentistry. Herein, we introduced a gel based on sanguiritrin, medicinal extracts of calendula and yarrow, and evaluated its effectiveness in the treatment of chronic simple marginal gingivitis in the clinical study involving 45 patients aged 18 to 23 years (26 females and 19 males). In the treatment group (23 patients), after professional oral hygiene and correction of hygiene skills, the dental gel based on sanguiritrin, medicinal extracts of calendula and yarrow was applied as part of complex therapy, while in the control group (22 patients) the Cholisal gel was used. The data obtained from hygienic and periodontal indices following the treatment (OHI-S — 0.39±0.03; PBI — 1.12±0.06; PMA — 16.4±1.31%) showed clinical anti-inflammatory efficacy of the introduced dental gel in the treatment of gingivitis, while positive indices dynamics of the dental status (OHI-S — 0.64±0.03; PBI — 0.42±0.03; PMA — 9.92±1.42%) evaluated in 3rd, 6th and 12th months after the therapy indicated of the stability of obtained results.