Technological developments in dielectrophoresis and its path to commercialization

Abstract

One of the bottlenecks for cell therapy development is the need to isolate specific cells, be it stem cells with specific differentiation fates, or specific white cells from a blood cell sort. However, the nature of the application means that the separation method should ideally be label-free and GMP- compliant, as well as achieving appropriate levels of throughput and cell recovery. One emergent field in cell separation is dielectrophoresis, an electrostatic method that has the potential to meet this growing need. Recent commercial developments mean that for the first time, this tech- nique will be more widely available to the cell therapy sector