Pre and Post Menstruation Cognitive Functioning in Women with remenstrual Dysphoric Disorder, Premenstrual Syndrome and Controls: A Quasi Experimental Study

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Abstract

Background: Inconsistent findings regarding the cognitive impact of Premenstrual Syndrome (PMS) and Premenstrual Dysphoric Disorder (PMDD) limit understanding of their effects on women’s daily lives. These inconsistencies may arise from neglecting menstrual phase in cognitive assessments. Considering the significant impact of PMS/PMDD on work, academics, and relationships, clarifying their cognitive effects is essential for targeted interventions and improved quality of life. This study investigates the cognitive impacts of these conditions, focusing on the influence of menstrual phase. Methods: Using a Google Form for initial data collection, 60 participants (mean age 24.47) were categorized into Control, PMS, and PMDD groups based on their responses. Cognitive performance was gauged using the Montreal Cognitive Assessment (MoCA), administered during two distinct menstrual phases: luteal and follicular. Results: Key findings revealed pronounced cognitive differences across these phases, with the most significant disparities observed in the PMDD group, suggesting a gradient effect where PMDD individuals exhibited the most considerable cognitive shifts (p

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Rabbani, H., Irfan, S., & Khanum, S. (2025). Pre and Post Menstruation Cognitive Functioning in Women with remenstrual Dysphoric Disorder, Premenstrual Syndrome and Controls: A Quasi Experimental Study. BMC Women’s Health, 25(1). https://doi.org/10.1186/s12905-025-04103-5

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