Is it more accurate to measure the absolute or the relative change of new high or ultrasensitive troponin assays to diagnose acute myocardial infarction?

Abstract

Clinical questionIn emergency department patients with symptoms suggestive of acute myocardial infarction, is the absolute or relative change of cardiac troponin assays (either high sensitivity or ultrasenstive) more accurate in diagnosing acute myocardial infarction at 1 to 2 hours postpresentation?Article chosenRechlin T, Ifran A, Twerenbold R, et al. Utility of absolute and relative changes in cardiac troponin concentrations in the early diagnosis of acute myocardial infarction. Circulation 2011;124:136-45.ObjectiveTo evaluate the accuracy of new troponin assays in diagnosing acute myocardial events.