Abstract
We report the development of a potent, selective histone deacetylase 6 (HDAC6) inhibitor. This HDAC6 inhibitor blocks growth of normal and transformed cells but does not induce death of normal cells. The HDAC6 inhibitor alone is as effective as paclitaxel in anticancer activity in tumor-bearing mice.
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CITATION STYLE
APA
Lee, J. H., Yao, Y., Mahendran, A., Ngo, L., Venta-Perez, G., Choy, M. L., … Marks, P. A. (2015). Development of a histone deacetylase 6 inhibitor and its biological effects. Proceedings of the National Academy of Sciences of the United States of America, 112(39), 12005–12010. https://doi.org/10.1073/pnas.1515882112
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