Synthesis and biological activity of some new pyrazoline and pyrrolo[3,4-c]pyrazole-4,6-dione derivatives: Reaction of nitrilimines with some dipolarophiles

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Abstract

Several 1,3-diaryl-5-(cyano-, aminocarbonyl- and ethoxycarbonyl-)-2- pyrazoline, pyrrolo[3,4-c]pyrazole-4,6-dione and 1,3,4,5-tetraaryl-2-pyrazoline derivatives were prepared by the reaction of nitrilimine with different dipolarophilic reagents. The new compounds were characterized using IR, 1H-NMR, 13C-NMR and mass spectra. Biological screening of some compounds is reported. © 2008 by MDPI.

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Abunada, N. M., Hassaneen, H. M., Kandile, N. G., & Miqdad, O. A. (2008). Synthesis and biological activity of some new pyrazoline and pyrrolo[3,4-c]pyrazole-4,6-dione derivatives: Reaction of nitrilimines with some dipolarophiles. Molecules, 13(4), 1011–1024. https://doi.org/10.3390/molecules13041011

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