A highly selective phenothiazine-based fluorescence 'turn-on' indicator based on cyanide-promoted novel protection/deprotection mechanism

Abstract

A cyanide anion (CN-)-triggered deprotection of NH-protected phenothiazine, (E)-10-(10H-phenothiazin-3′-yl)propenal, has been discovered as a novel mechanism for the highly selective fluorescence detection of CN- under ambient conditions. The present protocol may pave the way for its broad application in organic synthesis in the near future. This journal is